Nucleic Acids Research - current
订阅

最新

1. Novel function of U7 snRNA in the repression of HERV1/LTR12s and lincRNAs in human cells
2. ADARp150 counteracts whole genome duplication
3. The molecular mechanism for TERRA recruitment and annealing to telomeres
4. Cryo-EM structure of DNA polymerase of African swine fever virus
5. CRISPR-Cas target recognition for sensing viral and cancer biomarkers
6. Systematic discovery of DNA-binding tandem repeat proteins
7. Correction to ‘DNA sequence and chromatin differentiate sequence-specific transcription factor binding in the human malaria parasite Plasmodium falciparum’
8. Clinically relevant mutations in regulatory regions of metabolic genes facilitate early adaptation to ciprofloxacin in Escherichia coli
9. Methods for constructing and evaluating consensus genomic interval sets
10. Structural basis of Cas3 activation in type I-C CRISPR-Cas system
11. N-terminal domain of polypyrimidine-tract binding protein is a dynamic folding platform for adaptive RNA recognition
12. Structural insights into RNA cleavage by a novel family of bacterial RNases
13. Network medicine-based epistasis detection in complex diseases: ready for quantum computing
14. RudS: bacterial desulfidase responsible for tRNA 4-thiouridine de-modification
15. The SAVED domain of the type III CRISPR protease CalpL is a ring nuclease
16. Rapid profiling of transcription factor–cofactor interaction networks reveals principles of epigenetic regulation
17. Efficient circularization of protein-encoding RNAs via a novel cis-splicing system
18. An integrated machine-learning model to predict nucleosome architecture
19. Chemical synthesis of 2″OMeNAD+ and its deployment as an RNA 2′-phosphotransferase (Tpt1) ‘poison’ that traps the enzyme on its abortive RNA-2′-PO4-(ADP-2″OMe-ribose) reaction intermediate
20. The enhancer RNA, AANCR, regulates APOE expression in astrocytes and microglia
21. Metabolic RNA labeling in non-engineered cells following spontaneous uptake of fluorescent nucleoside phosphate analogues
22. NucleoFind: a deep-learning network for interpreting nucleic acid electron density
23. Meiotic chromatin-associated HSF5 is indispensable for pachynema progression and male fertility
24. Y-switch: a spring-loaded synthetic gene switch for robust DNA/RNA signal amplification and detection
25. Improved sub-genomic RNA prediction with the ARTIC protocol
26. A phage satellite manipulates the viral DNA packaging motor to inhibit phage and promote satellite spread
27. Template-independent synthesis and 3′-end labelling of 2′-modified oligonucleotides with terminal deoxynucleotidyl transferases
28. Genetic–epigenetic interplay in the determination of plant 3D genome organization
29. Rational design of base, sugar and backbone modifications improves ADAR-mediated RNA editing
30. The C-terminal 4CXXC-type zinc finger domain of CDCA7 recognizes hemimethylated DNA and modulates activities of chromatin remodeling enzyme HELLS
31. DNA damage-induced phosphorylation of a replicative DNA helicase results in inhibition of DNA replication through attenuation of helicase function
32. Senataxin RNA/DNA helicase promotes replication restart at co-transcriptional R-loops to prevent MUS81-dependent fork degradation
33. Invention of circRNA promoting RNA to specifically promote circRNA production
34. Transposition with Tn3-family elements occurs through interaction with the host β-sliding clamp processivity factor
35. Advancing quantitative PCR with color cycle multiplex amplification
36. Discovery of numerous novel Helitron-like elements in eukaryote genomes using HELIANO
37. Efficacy, biodistribution and safety comparison of chemically modified antisense oligonucleotides in the retina
38. Redundant but essential functions of PARP1 and PARP2 in DNA ligase I-independent DNA replication
39. Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase γ
40. The characteristics of CTCF binding sequences contribute to enhancer blocking activity
41. A novel interaction between the 5′ untranslated region of the Chikungunya virus genome and Musashi RNA binding protein is essential for efficient virus genome replication
42. PHF8 facilitates transcription recovery following DNA double-strand break repair
43. Trypanosome mRNA recapping is triggered by hypermethylation originating from cap 4
44. The RNA helicase DDX39 contributes to the nuclear export of spliceosomal U snRNA by loading of PHAX onto RNA
45. A new approach to RNA synthesis: immobilization of stably and functionally co-tethered promoter DNA and T7 RNA polymerase
46. Cas9 interaction with the tracrRNA nexus modulates the repression of type II-A CRISPR-cas genes
47. High resolution landscape of ribosomal RNA processing and surveillance
48. Molecular basis for cA6 synthesis by a type III-A CRISPR–Cas enzyme and its conversion to cA4 production
49. tRNA expression and modification landscapes, and their dynamics during zebrafish embryo development
50. DNA sequence and chromatin differentiate sequence-specific transcription factor binding in the human malaria parasite Plasmodium falciparum
51. ENL reads histone β-hydroxybutyrylation to modulate gene transcription
更新于 16 分钟前

近期历史最近 100 条记录

2024-09-23 Novel function of U7 snRNA in the repression of HERV1/LTR12s and lincRNAs in human cells
2024-09-23 ADARp150 counteracts whole genome duplication
2024-09-23 The molecular mechanism for TERRA recruitment and annealing to telomeres
2024-09-23 Cryo-EM structure of DNA polymerase of African swine fever virus
2024-09-23 CRISPR-Cas target recognition for sensing viral and cancer biomarkers
2024-09-23 Systematic discovery of DNA-binding tandem repeat proteins
2024-09-23 Correction to ‘DNA sequence and chromatin differentiate sequence-specific transcription factor binding in the human malaria parasite Plasmodium falciparum’
2024-09-23 Clinically relevant mutations in regulatory regions of metabolic genes facilitate early adaptation to ciprofloxacin in Escherichia coli
2024-09-23 Methods for constructing and evaluating consensus genomic interval sets
2024-09-23 Structural basis of Cas3 activation in type I-C CRISPR-Cas system
2024-09-23 N-terminal domain of polypyrimidine-tract binding protein is a dynamic folding platform for adaptive RNA recognition
2024-09-23 Structural insights into RNA cleavage by a novel family of bacterial RNases
2024-09-23 Network medicine-based epistasis detection in complex diseases: ready for quantum computing
2024-09-23 RudS: bacterial desulfidase responsible for tRNA 4-thiouridine de-modification
2024-09-23 The SAVED domain of the type III CRISPR protease CalpL is a ring nuclease
2024-09-23 Rapid profiling of transcription factor–cofactor interaction networks reveals principles of epigenetic regulation
2024-09-23 Efficient circularization of protein-encoding RNAs via a novel cis-splicing system
2024-09-23 An integrated machine-learning model to predict nucleosome architecture
2024-09-23 Chemical synthesis of 2″OMeNAD+ and its deployment as an RNA 2′-phosphotransferase (Tpt1) ‘poison’ that traps the enzyme on its abortive RNA-2′-PO4-(ADP-2″OMe-ribose) reaction intermediate
2024-09-23 The enhancer RNA, AANCR, regulates APOE expression in astrocytes and microglia
2024-09-23 Metabolic RNA labeling in non-engineered cells following spontaneous uptake of fluorescent nucleoside phosphate analogues
2024-09-23 NucleoFind: a deep-learning network for interpreting nucleic acid electron density
2024-09-23 Meiotic chromatin-associated HSF5 is indispensable for pachynema progression and male fertility
2024-09-23 Y-switch: a spring-loaded synthetic gene switch for robust DNA/RNA signal amplification and detection
2024-09-23 Improved sub-genomic RNA prediction with the ARTIC protocol
2024-09-23 A phage satellite manipulates the viral DNA packaging motor to inhibit phage and promote satellite spread
2024-09-23 Template-independent synthesis and 3′-end labelling of 2′-modified oligonucleotides with terminal deoxynucleotidyl transferases
2024-09-23 Genetic–epigenetic interplay in the determination of plant 3D genome organization
2024-09-23 Rational design of base, sugar and backbone modifications improves ADAR-mediated RNA editing
2024-09-23 The C-terminal 4CXXC-type zinc finger domain of CDCA7 recognizes hemimethylated DNA and modulates activities of chromatin remodeling enzyme HELLS
2024-09-23 DNA damage-induced phosphorylation of a replicative DNA helicase results in inhibition of DNA replication through attenuation of helicase function
2024-09-23 Senataxin RNA/DNA helicase promotes replication restart at co-transcriptional R-loops to prevent MUS81-dependent fork degradation
2024-09-23 Invention of circRNA promoting RNA to specifically promote circRNA production
2024-09-23 Transposition with Tn3-family elements occurs through interaction with the host β-sliding clamp processivity factor
2024-09-23 Advancing quantitative PCR with color cycle multiplex amplification
2024-09-23 Discovery of numerous novel Helitron-like elements in eukaryote genomes using HELIANO
2024-09-23 Efficacy, biodistribution and safety comparison of chemically modified antisense oligonucleotides in the retina
2024-09-23 Redundant but essential functions of PARP1 and PARP2 in DNA ligase I-independent DNA replication
2024-09-23 Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase γ
2024-09-23 The characteristics of CTCF binding sequences contribute to enhancer blocking activity
2024-09-23 A novel interaction between the 5′ untranslated region of the Chikungunya virus genome and Musashi RNA binding protein is essential for efficient virus genome replication
2024-09-23 PHF8 facilitates transcription recovery following DNA double-strand break repair
2024-09-23 Trypanosome mRNA recapping is triggered by hypermethylation originating from cap 4
2024-09-23 The RNA helicase DDX39 contributes to the nuclear export of spliceosomal U snRNA by loading of PHAX onto RNA
2024-09-23 A new approach to RNA synthesis: immobilization of stably and functionally co-tethered promoter DNA and T7 RNA polymerase
2024-09-23 Cas9 interaction with the tracrRNA nexus modulates the repression of type II-A CRISPR-cas genes
2024-09-23 High resolution landscape of ribosomal RNA processing and surveillance
2024-09-23 Molecular basis for cA6 synthesis by a type III-A CRISPR–Cas enzyme and its conversion to cA4 production
2024-09-23 tRNA expression and modification landscapes, and their dynamics during zebrafish embryo development
2024-09-23 DNA sequence and chromatin differentiate sequence-specific transcription factor binding in the human malaria parasite Plasmodium falciparum
2024-09-23 ENL reads histone β-hydroxybutyrylation to modulate gene transcription
2024-09-09 MADDD-seq, a novel massively parallel sequencing tool for simultaneous detection of DNA damage and mutations
2024-09-09 A new perspective on microRNA-guided gene regulation specificity, and its potential generalization to transcription factors and RNA-binding proteins
2024-09-09 Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch
2024-09-09 Induction of bacterial expression at the mRNA level by light
2024-09-09 Discovery of antiphage systems in the lactococcal plasmidome
2024-09-09 Highly sensitive mapping of in vitro type II topoisomerase DNA cleavage sites with SHAN-seq
2024-09-09 H3T11 phosphorylation by CKII is required for heterochromatin formation in Neurospora
2024-09-09 Stress granule formation helps to mitigate neurodegeneration
2024-09-09 Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells
2024-09-09 CRISPR perfect adaptation for robust control of cellular immune and apoptotic responses
2024-09-09 Loss of the DNA repair protein, polynucleotide kinase/phosphatase, activates the type 1 interferon response independent of ionizing radiation
2024-09-09 High-throughput determination of RNA tertiary contact thermodynamics by quantitative DMS chemical mapping
2024-09-09 CoPixie, a novel algorithm for single-particle track colocalization, enables efficient quantification of telomerase dynamics at telomeres
2024-09-09 TRF2–RAP1 represses RAD51-dependent homology-directed telomere repair by promoting BLM-mediated D-loop unwinding and inhibiting BLM–DNA2-dependent 5′-end resection
2024-09-09 High ionic strength vector formulations enhance gene transfer to airway epithelia
2024-09-09 Quantifying allele-specific CRISPR editing activity with CRISPECTOR2.0
2024-09-09 Unraveling the structure and function of a novel SegC protein interacting with the SegAB chromosome segregation complex in Archaea
2024-09-09 The complete pathway for co-transcriptional mRNA maturation within a large protein of a non-segmented negative-strand RNA virus
2024-09-09 Engineered transcription activator-like effector dimer proteins confer DNA loop-dependent gene repression comparable to Lac repressor
2024-09-09 Solution structures and effects of a platinum compound successively bound MYC G-quadruplex
2024-09-09 Understanding the relationship between sequences and kinetics of DNA strand displacements
2024-09-09 Structural insights into the assembly of type IIA topoisomerase DNA cleavage-religation center
2024-09-09 The cullin Rtt101 promotes ubiquitin-dependent DNA−protein crosslink repair across the cell cycle
2024-09-09 The translesion polymerase Pol Y1 is a constitutive component of the B. subtilis replication machinery
2024-09-09 Molecular basis of RNA recombination in the 3′UTR of chikungunya virus genome
2024-09-09 RNA encoded peptide barcodes enable efficient in vivo screening of RNA delivery systems
2024-09-09 HYENA detects oncogenes activated by distal enhancers in cancer
2024-09-09 A UTP3-dependent nucleolar translocation pathway facilitates pre-rRNA 5′ETS processing
2024-09-09 The human mitochondrial translation factor TACO1 alleviates mitoribosome stalling at polyproline stretches
2024-09-09 ADBP-1 regulates ADR-2 nuclear localization to control editing substrate selection
2024-09-09 CRISPR-Cas12a exhibits metal-dependent specificity switching
2024-09-09 Sampling globally and locally correct RNA 3D structures using Ernwin, SPQR and experimental SAXS data
2024-09-09 Differential processing of RNA polymerase II at DNA damage correlates with transcription-coupled repair syndrome severity
2024-09-09 DNA cytosine methyltransferases differentially regulate genome-wide hypermutation and interhomolog recombination in Trichoderma reesei meiosis
2024-09-09 Instability throughout the Saccharomyces cerevisiae genome resulting from Pms1 endonuclease deficiency
2024-09-09 CLOCI: unveiling cryptic fungal gene clusters with generalized detection
2024-09-09 GSearch: ultra-fast and scalable genome search by combining K-mer hashing with hierarchical navigable small world graphs
2024-09-09 Adenovirus small E1A directs activation of Alu transcription at YAP/TEAD- and AP-1-bound enhancers through interactions with the EP400 chromatin remodeler
2024-09-09 The critical role of the iron–sulfur cluster and CTC components in DOG-1/BRIP1 function in Caenorhabditis elegans
2024-09-09 SMCHD1 activates the expression of genes required for the expansion of human myoblasts
2024-09-09 Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference
2024-09-09 CyCoNP lncRNA establishes cis and trans RNA–RNA interactions to supervise neuron physiology
2024-09-09 BOD1L mediates chromatin binding and non-canonical function of H3K4 methyltransferase SETD1A
2024-09-09 Small RNA-mediated genetic switches coordinate ALG-3/4 small RNA pathway function
2024-09-09 Asymmetric bulges within hairpin RNA transgenes influence small RNA size, secondary siRNA production and viral defence
2024-09-09 RESC14 and RESC8 cooperate to mediate RESC function and dynamics during trypanosome RNA editing
2024-09-09 Structure and RNA-binding of the helically extended Roquin CCCH-type zinc finger
2024-09-09 Phosphorylation of the nuclear poly(A) binding protein (PABPN1) during mitosis protects mRNA from hyperadenylation and maintains transcriptome dynamics
2024-09-09 Resolution of ribosomal stalling by EF-P and ABCF ATPases YfmR and YkpA/YbiT

匿名用户只展示最新 100 条榜单历史,更多历史数据请登录后查看,支持时光机按天筛选