Gastroenterology
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1. Eosinophils are just the tip of the iceberg for eosinophilic esophagitis Eric E. Low, Rena Yadlapati
2. The first approved therapy in infants and young children with EoE – now the big question: where will dupilumab fit into real-world practice? Eric E. Low, Rena Yadlapati
3. Immune checkpoint inhibitor induced colitis Anusha S. Thomas, Yang Lu, Mathew Campbell, John A. Thompson, Dongfeng Tan, David M. Faleck, Yinghong Wang
4. Persistent severe abdominal pain in a 40-year-old male patient Shin Kashima, Yuki Kamikokura, Kentaro Moriichi
5. Engineering therapeutic Tregs to overexpress GPR15 improves functional fitness for in vivo gut homing Tanja M. Müller, Li-Juan Liu, Manuel Wiesinger, TRR241 Working Group, Markus F. Neurath, Caroline J. Voskens, Sebastian Zundler
6. Novel immune manipulators for IBD: miniproteins! Eytan Wine
7. Early Life Exposure to Parental Crohn's disease is Associated with Offspring’s Gut Microbiome, Gut Permeability and Increased Risk of Future Crohn's Disease Sun-Ho Lee, Maham Bushra, Lanhui Qiu, Anne M. Griffiths, Williams Turpin, Kenneth Croitoru, Crohn’s Colitis Canada-GEM consortium
8. The Educational Impact of the GI Hospitalist Model on Gastroenterology Fellowship Training Ryan Flanagan, Calley Levine, Kenneth Hung, Michelle Hughes, Cassandra D.L. Fritz, David Wan, Daniel J. Stein
9. Safety and Tolerability of CP101, a full spectrum, oral microbiome therapeutic for the prevention of recurrent C. difficile infection: A Phase 2 Randomized Controlled Trial. Jessica R. Allegretti, Colleen R. Kelly, Thomas Louie, Monika Fischer, Susy Hota, Bharat Misra, Nick W. Van Hise, Eugene Yen, Jeffrey S. Bullock, Michael Silverman, Ian Davis, Sarah K. McGill, Darrell S. Pardi, Robert Orenstein, Ari Grinspan, Najwa El-Nachef, Paul Feuerstadt, Thomas J. Borody, Sahil Khanna S, Shrish Budree, Zain Kassam
10. Use of Large Language Models to Identify Surveillance Colonoscopy Intervals – A Feasibility Study Vedant Acharya, Vignesh Kumaresan, Jonathan England, Shivan Mehta, Daniel Sussman, Amar Deshpande
11. CME Exam 1: Effect of Brain-Gut Behavioral Treatments on Abdominal Pain in Irritable Bowel Syndrome: Systematic Review and Network Meta-Analysis
12. CME Exam 2: Prognostic Factors for Early Recurrence After Resection of Pancreatic Cancer: A Systematic Review and Meta-Analysis
13. Interventions to Increase Follow-Up of Abnormal Stool-Based Colorectal Cancer Screening Tests in Safety Net Settings: A Systematic Review Rachel B. Issaka, Ari Bell-Brown, Teresa Jewell, Sara L. Jackson, Bryan J. Weiner
14. Cover 1
15. Editorial Board
16. Elsewhere in The AGA Journals (Preview Section)
17. Table of Contents
18. Corrigendum
19. Hidden Footprints in Ascites: Lessons from a Mystery Enduring for 200 Years Yoichi Nakatsu, Makoto Furihata, Taro Osada
20. A brain-gut pathway for stress-induced microbiome changes Sarah A. Najjar, Kara Gross Margolis
21. Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4+ T cells as predictors for response to integrin α4β7-blocking therapy in inflammatory bowel disease Veronika Horn, Camila A. Cancino, Lisa Maria Steinheuer, Benedikt Obermayer, Konstantin Fritz, Anke L. Nguyen, Kim Susan Juhran, Christina Plattner, Diana Bösel, Lotte Oldenburg, Marie Burns, Axel Ronald Schulz, Mariia Saliutina, Eleni Mantzivi, Donata Lissner, Thomas Conrad, Mir-Farzin Mashreghi, Sebastian Zundler, Elena Sonnenberg, Michael Schumann, Lea-Maxie Haag, Dieter Beule, Lukas Flatz, TRR241 IBDome Consortium, Zlatko Trjanoski, Geert D’Haens, Carl Weidinger, Henrik E. Mei, Britta Siegmund, Kevin Thurley, Ahmed N. Hegazy
22. Surveillance for hepatocellular carcinoma in cirrhosis: End of monopoly for serum alpha fetoprotein Lung-Yi Mak, Man-Fung Yuen
23. It Runs in the Family: What Studying Unaffected Individuals in Simplex and Multiplex Families Tells Us About IBD Development Jonas J. Rudbaek, Aleksejs Sazonovs, Tine Jess
24. The Impact of Population-Based Helicobacter pylori Test-To-Treat Strategies on Gastric Cancer Outcomes Corey J. Ketchem
25. Methodological Aspects of "Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention: A Randomized Placebo-Controlled Trial" Manjeet Kumar Goyal, Karan Sachdeva, Omesh Goyal
26. Evaluating Research Strategy and Inclusion Criteria of Long-term Proton Pump Inhibitor Use Yanqing Niu, Xiaherezhati Aihaiti, Man Li
27. Reply Hanseul Kim, Long H. Nguyen
28. Reply to Iovino et al, Goyal et al, Zhu, Guo et al, and Tian et al Fernando Azpiroz
29. Interventions for Improving Quality of Colonoscopy Qing-Hua Wang, Min Zhang, Hua Chen, Wei Han
30. Advancing Biofeedback Therapy in Abdominal Distention: Recommendations for Methodological Improvements and Increased Generalizability Xiaolong Guo, Yongfeng Wang, Yuan Yuan
31. Refining Biofeedback in Gastroenterology: Enhancing Precision in Thoracoabdominal Motion Studies Junkun Zhu
32. Focus on Psychological Intervention: Insights from Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention Chenhong Tian, Changlin Zhai, Haihua Pan
33. Reply Anna-Klara Wiklund, Giola Santoni, Jesper Lagergren
34. Helicobacter pylori Eradication Treatment Might Help Reduce the Risk of Esophageal Adenocarcinoma Hui Chen, Chuanli Ren
35. Enhancing Research on Helicobacter pylori Eradication and Esophageal Adenocarcinoma Risk: A Call for Broader Studies and Methodological Rigor Xiaolong Guo, Yongfeng Wang, Hui Cai
36. Detection of Gastrointestinal Bleeding with Large Language Models to Aid Quality Improvement and Appropriate Reimbursement Neil S. Zheng, Vipina K. Keloth, Kisung You, Daniel Kats, Darrick K. Li, Ohm Deshpande, Hamita Sachar, Hua Xu, Loren Laine, Dennis L. Shung
37. Obesity facilitated colon cancer progression is mediated by increased diacylglycerol o-acyltransferases 1 and 2 (DGAT1/2) levels Jenisha Ghimire, Morgan E. Collins, Patricia Snarski, Angelle N. King, Emmanuelle Ruiz, Rida Iftikhar, Harrison M. Penrose, Krzysztof Moroz, Tyler Rorison, Melody Baddoo, Muhammad Anas Naeem, Arnold H. Zea, Scott T. Magness, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
38. Myosin Vb Traffics P-glycoprotein to the Apical Membrane of Intestinal Epithelial Cells Sarah A. Dooley, Elena Kolobova, Andreanna Burman, Izumi Kaji, Jessica R. Digrazia, Rachel Stubler, Anna Goldstein, Charulekha Packirisamy, Alexander W. Coutts, Milena Saqui-Salces, Nan Gao, Melinda A. Engevik, Mitchell D. Shub, James R. Goldenring, Amy C. Engevik
39. A Phase 3 Biomarker Validation of GALAD for the Detection of Hepatocellular Carcinoma in Cirrhosis Tracey L. Marsh, Neehar D. Parikh, Lewis R. Roberts, Myron E. Schwartz, Mindie H. Nguyen, Alex Befeler, Stephanie Page-Lester, Nabihah Tayob, Sudhir Srivastava, Jo Ann Rinaudo, Amit G. Singal, K. Rajender Reddy, Jorge A. Marrero
40. The Brain and the Immune System: A Dynamic Duo in Detecting and Defending Lin Y. Hung, Kara Gross Margolis
41. Comments on “Diagnosis and Management of Pancreatic Cysts” Santhi Swaroop Vege
42. Reply Timothy B. Gardner, Walter G. Park, Peter J. Allen
43. Dual Targeting of Syndecan-1 and Glucose Transporter-1 With a Novel Lipid-Based Delivery System Enhances Therapeutic Efficacy and Overcomes Chemoresistance in Pancreatic Ductal Adenocarcinoma Hari Krishna Rachamala, Naga Malleswara Rao Nakka, Ramcharan Singh Angom, Santanu Bhattacharya, Krishnendu Pal, Debabrata Mukhopadhyay
44. Reevaluating stemness in the intestinal crypt Samuel Asfaha, Nicola L. Jones
45. Stress Ulcer Prophylaxis in the Intensive Care Unit – More Evidence of Benefit Rishad Khan
46. EUS-guided Rendezvous versus Needle-knife Sphincterotomy Following Difficult Biliary Cannulation in ERCP for Benign Disease Nauzer Forbes
47. Where do non-invasive colorectal cancer tools ‘FIT’ alongside colonoscopy in the surveillance of high-risk patients? Kevin J. Monahan
48. AGA Clinical Practice Update on Integrating Potassium-Competitive Acid Blockers Into Clinical Practice: Expert Review Amit Patel, Loren Laine, Paul Moayyedi, Justin Wu
49. Portal Fibrosis and the Ductular Reaction: Pathophysiological Role in the Progression of Liver Disease and Translational Opportunities Vikas Gupta, Tejasav S. Sehrawat, Massimo Pinzani, Mario Strazzabosco
50. A Head-to Head Comparison of Risankizumab and Ustekinumab as Second-Line Therapy in Moderate to Severely Active Crohn’s Disease Pavel S. Roshanov, Reena Khanna
51. Reply Ali Rezaie, Yee Hui Yeo
52. Risankizumab for Induction and Maintenance of Remission in Ulcerative Colitis Pavel S. Roshanov, Reena Khanna
53. Proteomic Biomarkers in Serum Predict Villous Atrophy Development in Asymptomatic Potential Celiac Disease Children at Time of Diagnosis Renata Auricchio, Roberta Mandile, Janneke Samsom, Chiara Esposito, Rossella de Cegli, Luigi Greco, European Laboratory for Food Induced Disease (ELFID) Group
54. Pragmatic Resect and Discard Implementation Using Computer-Assisted Optical Polyp Diagnosis Mahsa Taghiakbari, Douglas K. Rex, Heiko Pohl, Roupen Djinbachian, Felix Huang, Cesare Hassan, Daniel Von Renteln
55. Reply Laurens A. Van Kleef, Willem Pieter Brouwer
56. Glucagon-Like Peptide 1 Receptor Agonists and Risk of Adverse Anesthesia Events: Caution Warranted When Interpreting Associations With Pulmonary Aspiration Inuk Zandvakili, Wei-Wen Hsu, Gregory G. Ginsberg
57. Comments on “Metabolic Dysfunction–Associated Fibrosis 5 (MAF-5) Score Predicts Liver Fibrosis Risk and Outcome in the General Population With Metabolic Dysfunction” Yuting Guan, Jiaming Yang, Zudong Xu
58. With Great Statistical Power Comes Great Responsibility: Pitfalls of Claims Database Research on the Periprocedural GLP-1 Receptor Agonist Management Debate Brent Hiramoto, Thomas R. Mccarty, Mayssan Muftah, Walter W. Chan
59. Tofu-like Disfiguring Colitis Nie Kai, Zhao Lian, Wang Xiaoyan
60. Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have a Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn’s Disease Pablo A. Olivera, Helena Martinez-Lozano, Haim Leibovitzh, Mingyue Xue, Anna Neustaeter, Osvaldo Espin-Garcia, Wei Xu, Karen L. Madsen, David S. Guttman, Charles N. Bernstein, Baruch Yerushalmi, Jeffrey S. Hyams, Maria T. Abreu, John K. Marshall, Iwona Wrobel, David R. Mack, Kevan Jacobson, Alain Bitton, Guy Aumais, Remo Panacionne, Levinus A. Dieleman, Mark S. Silverberg, A. Hillary Steinhart, Paul Moayyedi, Dan Turner, Anne M. Griffiths, Williams Turpin, Sun-Ho Lee, Kenneth Croitoru, Crohn’s and Colitis Canada (CCC) Genetic, Environmental, Microbial (GEM) Project Research Consortium
61. Intestinal Permeability in Disorders of Gut-Brain Interaction: From Bench to Bedside Madhusudan Grover, Tim Vanuytsel, Lin Chang
62. Unveiling Cancer-Related Metaplastic Cells in Both Helicobacter pylori Infection and Autoimmune Gastritis Stella G. Hoft, Michelle Brennan, Javier A. Carrero, Nicholas M. Jackson, Challen A. Pretorius, Tarin M. Bigley, José B. Sáenz, Richard J. DiPaolo
63. Management of Small Bowel Crohn’s Disease Strictures: To Cut, to Stretch, or to Treat Inflammation? Cathy Lu, Brian G. Feagan, Joel G. Fletcher, Mark Baker, Stefan Holubar, Florian Rieder, Stenosis Therapy and Anti-Fibrosis Research Consortium
64. Stool-Based Testing for Post-Polypectomy Colorectal Cancer Surveillance Safely Reduces Colonoscopies: The Molecular Stool Testing for Colorectal Cancer Surveillance Study Beatriz Carvalho, Willemijn de Klaver, Francine van Wifferen, Meta C.J. van Lanschot, Alouisa J.P. van Wetering, Quirine E.W. van der Zander, Margriet Lemmens, Anne S. Bolijn, Marianne Tijssen, Pien Delis-van Diemen, Nikkie Buekers, Kathleen Daenen, Jaleesa van der Meer, Pauline G. van Mulligen, Brenda S. Hijmans, Sander de Ridder, Lana Meiqari, Mariska Bierkens, René W.M. van der Hulst, Johan P.H. Kuyvenhoven, Annemarie M. van Berkel, Annekatrien C.T.M. Depla, Monique E. van Leerdam, Jeroen M. Jansen, Caroline A. Wientjes, Jan-Willem A. Straathof, Eric T.P. Keulen, Dewkoemar Ramsoekh, Leon M.G. Moons, Michael Zacherl, Ad A.M. Masclee, Meike de Wit, Marjolein J.E. Greuter, Manon van Engeland, Evelien Dekker, Veerle M.H. Coupé, Gerrit A. Meijer
65. Pancreatic Cancer–Induced Metabolic Dysregulation Syndrome: Clinical Profile, Proposed Mechanisms, and Unanswered Questions Lanisha Patterson, Frederico G.S. Toledo, Anirban Maitra, Suresh T. Chari
66. Reply Roupen Djinbachian, Douglas K. Rex, Daniel Von Renteln
67. Reply Zainab Aziz, Sheila Rustgi, Chin Hur
68. Effectiveness and Cost-Effectiveness of Colorectal Cancer Screening With a Blood Test That Meets the Centers for Medicare and Medicaid Services Coverage Decision Amar K. Das, Craig Eagle, Amirali Talasaz
69. Corrigendum
70. Limitations in Autonomous Artificial Intelligence Optical Diagnosis Qi Mei, Poi Kuo, James Cheng-Chung Wei
71. A Rare Cause of liver injury in an adult Zixing Dai, Yuwen Li, Chuanlong Zhu
72. Reply Rosita Van Den Puttelaar, Pedro Nascimento De Lima, Iris Lansdorp-Vogelaar
73. Reply Uri Ladabaum, Ajitha Mannalithara, Robert E. Schoen, Jason A. Dominitz, David Lieberman
74. A Comparative Review of Autonomous Artificial Intelligence versus Artificial Intelligence–Assisted Human Optical Diagnosis of Colorectal Polyps Tiantian Cao, Chengqian Zhong
75. Combining Colonoscopy With Fecal Immunochemical Test Can Improve Current Familial Colorectal Cancer Colonoscopy Surveillance: A Modelling Study Francine Van Wifferen, Marjolein J.E. Greuter, Monique E. van Leerdam, Marcel B.W. Spanier, Evelien Dekker, Hans F.A. Vasen, Iris Lansdorp-Vogelaar, Karen Canfell, Gerrit A. Meijer, Tanya M. Bisseling, Nicoline Hoogerbrugge, Veerle M.H. Coupé
76. Development and Validation of an Integrative Risk Score for Future Risk of Crohn’s Disease in Healthy First-Degree Relatives: A Multicentre Prospective Cohort Study Sun-Ho Lee, Williams Turpin, Osvaldo Espin-Garcia, Wei Xu, Kenneth Croitoru, Crohn’s Colitis Canada-Genetic, Environmental, Microbial Project Research Consortium
77. Reply Roupen Djinbachian, Douglas K. Rex, Daniel Von Renteln
78. Corrigendum
79. Recompensation of Chronic Hepatitis C–Related Decompensated Cirrhosis Following Direct-Acting Antiviral Therapy: Prospective Cohort Study From a Hepatitis C Virus Elimination Program Madhumita Premkumar, Radha K. Dhiman, Ajay Duseja, Rohit Mehtani, Sunil Taneja, Ekta Gupta, Pankaj Gupta, Anchal Sandhu, Prerna Sharma, Sahaj Rathi, Nipun Verma, Anand V. Kulkarni, Harish Bhujade, Sreedhara B. Chaluvashetty, Naveen Kalra, Gagandeep S. Grover, Jasvinder Nain, K. Rajender Reddy
80. Exon-Skipping–Based Subtyping of Colorectal Cancers Aslihan Ambeskovic, Matthew N. McCall, Jonathan Woodsmith, Hartmut Juhl, Hartmut Land
81. Glutamine Supplementation as a Novel Metabolic Therapeutic Strategy for LIG3-Dependent Chronic Intestinal Pseudo-obstruction Chiara Diquigiovanni, Nicola Rizzardi, Erica Cataldi-Stagetti, Livia Gozzellino, Federica Isidori, Francesca Valenti, Arianna Orsini, Annalisa Astolfi, Tania Giangregorio, Loris Pironi, Elisa Boschetti, Serena Arrigo, Alessandra Maresca, Penelope Magnoni, Anna Costanzini, Valerio Carelli, Mariko Taniguchi-Ikeda, Romana Fato, Christian Bergamini, Roberto De Giorgio, Elena Bonora
82. Crohn’s Patients and Healthy Infants Share Immunodominant B Cell Response to Commensal Flagellin Peptide Epitopes Qing Zhao, Lennard Wayne Duck, John T. Killian, Alexander F. Rosenberg, Peter J. Mannon, R. Glenn King, Lee A. Denson, Subra Kugathasan, Edward N. Janoff, Maria C. Jenmalm, Charles O. Elson
83. Unanticipated Findings With Upadacitinib Therapy Taylor A. Karl, McKinzie Johnson, Frank I. Scott
84. Gut Barrier Leakiness: Time to Take It Seriously? Javier Santos, Maria Rescigno
85. Dietary Pattern Linking to Intestinal Microbial Characteristics and Colorectal Cancer Risk Jun Sun
86. Endoscopic Gastric Fundal Mucosal Ablation Induces Weight Loss in Adults With Obesity Daniel B. Maselli, Lauren L. Donnangelo, Chase Wooley, Christopher Chapman, Vivek Kumbhari, Christopher E. Mcgowan
87. Effect of Enterotype-Dependent Stability of the Gut Microbiome on Postgastrectomy Malnutrition in Gastric Cancer Patients Han Na Oh, Woo Jun Sul, Sang-Yong Son, Sang-Uk Han, Hoon Hur, Sun Gyo Lim
88. Spatially Resolved Niche and Tumor Microenvironmental Alterations in Gastric Cancer Peritoneal Metastases Joseph J. Zhao, Chin-Ann Johnny Ong, Supriya Srivatsava, Daryl Kai Ann Chia, Haoran Ma, Kiekyon Huang, Taotao Sheng, Kalpana Ramnarayanan, Xuewen Ong, Su Ting Tay, Takeshi Hagihara, Angie Lay Keng Tan, Melissa Ching Ching Teo, Qiu Xuan Tan, Gillian Ng, Joey Wee-Shan Tan, Matthew Chau Hsien Ng, Yong Xiang Gwee, Robert Walsh, Jia Hao Law, Asim Shabbir, Guowei Kim, Yvonne Tay, Zhisheng Her, Giuseppe Leoncini, Bin Tean The, Jing Han Hong, Ryan Yong Kiat Tay, Chong Boon Teo, Mark P.G. Dings, Maarten Bijlsma, Jeffrey Huey Yew Lum, Sachin Mathur, Filippo Pietrantonio, Steven M. Blum, Hanneke van Laarhoven, Samuel J. Klempner, Wei Peng Yong, Jimmy Bok Yan So, Qingfeng Chen, Patrick Tan, Raghav Sundar
89. AGA Clinical Practice Update on Pregnancy-Related Gastrointestinal and Liver Disease: Expert Review Shivangi Kothari, Yalda Afshar, Lawrence S. Friedman, Joseph Ahn
90. Gluten-Dependent Activation of CD4+ T Cells by MHC Class II–Expressing Epithelium Sara Rahmani, Heather J. Galipeau, Alexandra V. Clarizio, Xuanyu Wang, Amber Hann, Gaston H. Rueda, Utkarshini N. Kirtikar, Marco Constante, Mark Wulczynski, Hsuan-Ming Su, Rebecca Burchett, Jonathan L. Bramson, Maria Ines Pinto-Sanchez, Juan Pablo Stefanolo, Sonia Niveloni, Michael G. Surette, Joseph A. Murray, Robert P. Anderson, Premysl Bercik, Alberto Caminero, Fernando G. Chirdo, Tohid F. Didar, Elena F. Verdu
91. Expanding the Diagnostic Toolkit in Chronic Cholestasis Nicholas Smith, Jennifer Borowsky, James A. Thomas
92. Development and Implementation of a Clinical Decision Support Tool to Improve Adherence to Colonoscopy Follow-Up Guidelines Brian A. Sullivan, Hochong Gilles, Lyndsey Knauf, Steve S. Choi, Jill Moore, Jason A. Dominitz
93. A Concerning Case of Severe Gastritis With Gastrointestinal Protein Loss Xinyu Liu, Hao Tang, Bei Tan
94. An Empirical Dietary Pattern Associated with the Gut Microbial Features in Relation to Colorectal Cancer Risk Kai Wang, Chun-Han Lo, Raaj S. Mehta, Long H. Nguyen, Yiqing Wang, Wenjie Ma, Tomotaka Ugai, Hidetaka Kawamura, Satoko Ugai, Yasutoshi Takashima, Kosuke Mima, Kota Arima, Kazuo Okadome, Marios Giannakis, Cynthia L. Sears, Jeffrey A. Meyerhardt, Kimmie Ng, Nicola Segata, Jacques Izard, Eric B. Rimm, Wendy S. Garrett, Curtis Huttenhower, Edward L. Giovannucci, Andrew T. Chan, Shuji Ogino, Mingyang Song
95. High Pathological Response Rate After Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer (NICHE-2 Study) Ville Sallinen
96. Reply Natalie Wilson, Mohammad Bilal, Aasma Shaukat
97. A MERFISHing Expedition for Colitis Jay R. Thiagarajah
98. Atlas of Metastatic Gastric Cancer Links Ferroptosis to Disease Progression and Immunotherapy Response Xiangdong Cheng, Enyu Dai, Jibo Wu, Natasha M. Flores, Yanshuo Chu, Ruiping Wang, Minghao Dang, Zhiyuan Xu, Guangchun Han, Yunhe Liu, Deyali Chatterjee, Can Hu, Jieer Ying, Yian Du, Litao Yang, Xiaoqing Guan, Shaowei Mo, Xuanye Cao, Guangsheng Pei, Jiahui Jiang, Xiaoyin Lu, Ana Morales Benitez, Rebecca E. Waters, Melissa Pool Pizzi, Namita Shanbhag, Yibo Fan, Fuduan Peng, Samir M. Hanash, George Calin, Andrew Futreal, Shumei Song, Cassian Yee, Pawel K. Mazur, Jiang-Jiang Qin, Jaffer A. Ajani, Linghua Wang
99. The Evolving Story of Blastocystis: From Foe to Friend Daniel Keszthelyi
100. Tofacitinib Uptake by Patient-Derived Intestinal Organoids Predicts Individual Clinical Responsiveness Kyung Ku Jang, David Hudesman, Drew R. Jones, P’ng Loke, Jordan E. Axelrad, Ken Cadwell, Tofacitinib Working Group
更新于 11 分钟前

近期历史最近 100 条记录

2024-10-09 Eosinophils are just the tip of the iceberg for eosinophilic esophagitis Eric E. Low, Rena Yadlapati
2024-10-09 The first approved therapy in infants and young children with EoE – now the big question: where will dupilumab fit into real-world practice? Eric E. Low, Rena Yadlapati
2024-10-09 Persistent severe abdominal pain in a 40-year-old male patient Shin Kashima, Yuki Kamikokura, Kentaro Moriichi
2024-10-09 Novel immune manipulators for IBD: miniproteins! Eytan Wine
2024-10-09 Engineering therapeutic Tregs to overexpress GPR15 improves functional fitness for in vivo gut homing Tanja M. Müller, Li-Juan Liu, Manuel Wiesinger, TRR241 Working Group, Markus F. Neurath, Caroline J. Voskens, Sebastian Zundler
2024-10-08 Immune checkpoint inhibitor induced colitis Anusha S. Thomas, Yang Lu, Mathew Campbell, John A. Thompson, Dongfeng Tan, David M. Faleck, Yinghong Wang
2024-10-08 Early Life Exposure to Parental Crohn's disease is Associated with Offspring’s Gut Microbiome, Gut Permeability and Increased Risk of Future Crohn's Disease Sun-Ho Lee, Maham Bushra, Lanhui Qiu, Anne M. Griffiths, Williams Turpin, Kenneth Croitoru, Crohn’s Colitis Canada-GEM consortium
2024-10-03 The Educational Impact of the GI Hospitalist Model on Gastroenterology Fellowship Training Ryan Flanagan, Calley Levine, Kenneth Hung, Michelle Hughes, Cassandra D.L. Fritz, David Wan, Daniel J. Stein
2024-10-02 Safety and Tolerability of CP101, a full spectrum, oral microbiome therapeutic for the prevention of recurrent C. difficile infection: A Phase 2 Randomized Controlled Trial. Jessica R. Allegretti, Colleen R. Kelly, Thomas Louie, Monika Fischer, Susy Hota, Bharat Misra, Nick W. Van Hise, Eugene Yen, Jeffrey S. Bullock, Michael Silverman, Ian Davis, Sarah K. McGill, Darrell S. Pardi, Robert Orenstein, Ari Grinspan, Najwa El-Nac
2024-10-02 Use of Large Language Models to Identify Surveillance Colonoscopy Intervals – A Feasibility Study Vedant Acharya, Vignesh Kumaresan, Jonathan England, Shivan Mehta, Daniel Sussman, Amar Deshpande
2024-10-01 Hidden Footprints in Ascites: Lessons from a Mystery Enduring for 200 Years Yoichi Nakatsu, Makoto Furihata, Taro Osada
2024-10-01 Corrigendum
2024-09-28 Surveillance for hepatocellular carcinoma in cirrhosis: End of monopoly for serum alpha fetoprotein Lung-Yi Mak, Man-Fung Yuen
2024-09-28 A brain-gut pathway for stress-induced microbiome changes Sarah A. Najjar, Kara Gross Margolis
2024-09-28 Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4+ T cells as predictors for response to integrin α4β7-blocking therapy in inflammatory bowel disease Veronika Horn, Camila A. Cancino, Lisa Maria Steinheuer, Benedikt Obermayer, Konstantin Fritz, Anke L. Nguyen, Kim Susan Juhran, Christina Plattner, Diana Bösel, Lotte Oldenburg, Marie Burns, Axel Ronald Schulz, Mariia Saliutina, Eleni Mantzivi, Donata Li
2024-09-26 It Runs in the Family: What Studying Unaffected Individuals in Simplex and Multiplex Families Tells Us About IBD Development Jonas J. Rudbaek, Aleksejs Sazonovs, Tine Jess
2024-09-26 The Impact of Population-Based Helicobacter pylori Test-To-Treat Strategies on Gastric Cancer Outcomes Corey J. Ketchem
2024-09-21 Methodological Aspects of "Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention: A Randomized Placebo-Controlled Trial" Manjeet Kumar Goyal, Karan Sachdeva, Omesh Goyal
2024-09-21 Reply to Iovino et al, Goyal et al, Zhu, Guo et al, and Tian et al Fernando Azpiroz
2024-09-21 Reply Hanseul Kim, Long H. Nguyen
2024-09-21 Evaluating Research Strategy and Inclusion Criteria of Long-term Proton Pump Inhibitor Use Yanqing Niu, Xiaherezhati Aihaiti, Man Li
2024-09-20 Refining Biofeedback in Gastroenterology: Enhancing Precision in Thoracoabdominal Motion Studies Junkun Zhu
2024-09-20 Advancing Biofeedback Therapy in Abdominal Distention: Recommendations for Methodological Improvements and Increased Generalizability Xiaolong Guo, Yongfeng Wang, Yuan Yuan
2024-09-20 Interventions for Improving Quality of Colonoscopy Qing-Hua Wang, Min Zhang, Hua Chen, Wei Han
2024-09-20 Enhancing Research on Helicobacter pylori Eradication and Esophageal Adenocarcinoma Risk: A Call for Broader Studies and Methodological Rigor Xiaolong Guo, Yongfeng Wang, Hui Cai
2024-09-20 Helicobacter pylori Eradication Treatment Might Help Reduce the Risk of Esophageal Adenocarcinoma Hui Chen, Chuanli Ren
2024-09-20 Reply Anna-Klara Wiklund, Giola Santoni, Jesper Lagergren
2024-09-20 Focus on Psychological Intervention: Insights from Thoracoabdominal Wall Motion–Guided Biofeedback Treatment of Abdominal Distention Chenhong Tian, Changlin Zhai, Haihua Pan
2024-09-19 Editorial Board
2024-09-19 Table of Contents
2024-09-19 Cover 1
2024-09-19 Interventions to Increase Follow-Up of Abnormal Stool-Based Colorectal Cancer Screening Tests in Safety Net Settings: A Systematic Review Rachel B. Issaka, Ari Bell-Brown, Teresa Jewell, Sara L. Jackson, Bryan J. Weiner
2024-09-19 CME Exam 2: Prognostic Factors for Early Recurrence After Resection of Pancreatic Cancer: A Systematic Review and Meta-Analysis
2024-09-19 Elsewhere in The AGA Journals (Preview Section)
2024-09-19 CME Exam 1: Effect of Brain-Gut Behavioral Treatments on Abdominal Pain in Irritable Bowel Syndrome: Systematic Review and Network Meta-Analysis
2024-09-18 Detection of Gastrointestinal Bleeding with Large Language Models to Aid Quality Improvement and Appropriate Reimbursement Neil S. Zheng, Vipina K. Keloth, Kisung You, Daniel Kats, Darrick K. Li, Ohm Deshpande, Hamita Sachar, Hua Xu, Loren Laine, Dennis L. Shung
2024-09-18 Myosin Vb Traffics P-glycoprotein to the Apical Membrane of Intestinal Epithelial Cells Sarah A. Dooley, Elena Kolobova, Andreanna Burman, Izumi Kaji, Jessica R. Digrazia, Rachel Stubler, Anna Goldstein, Charulekha Packirisamy, Alexander W. Coutts, Milena Saqui-Salces, Nan Gao, Melinda A. Engevik, Mitchell D. Shub, James R. Goldenring, Amy C
2024-09-18 Obesity facilitated colon cancer progression is mediated by increased diacylglycerol o-acyltransferases 1 and 2 (DGAT1/2) levels Jenisha Ghimire, Morgan E. Collins, Patricia Snarski, Angelle N. King, Emmanuelle Ruiz, Rida Iftikhar, Harrison M. Penrose, Krzysztof Moroz, Tyler Rorison, Melody Baddoo, Muhammad Anas Naeem, Arnold H. Zea, Scott T. Magness, Erik F. Flemington, Susan E. C
2024-09-16 A Phase 3 Biomarker Validation of GALAD for the Detection of Hepatocellular Carcinoma in Cirrhosis Tracey L. Marsh, Neehar D. Parikh, Lewis R. Roberts, Myron E. Schwartz, Mindie H. Nguyen, Alex Befeler, Stephanie Page-Lester, Nabihah Tayob, Sudhir Srivastava, Jo Ann Rinaudo, Amit G. Singal, K. Rajender Reddy, Jorge A. Marrero
2024-09-15 The Brain and the Immune System: A Dynamic Duo in Detecting and Defending Lin Y. Hung, Kara Gross Margolis
2024-09-15 Comments on “Diagnosis and Management of Pancreatic Cysts” Santhi Swaroop Vege
2024-09-15 Reply Timothy B. Gardner, Walter G. Park, Peter J. Allen
2024-09-14 Dual Targeting of Syndecan-1 and Glucose Transporter-1 With a Novel Lipid-Based Delivery System Enhances Therapeutic Efficacy and Overcomes Chemoresistance in Pancreatic Ductal Adenocarcinoma Hari Krishna Rachamala, Naga Malleswara Rao Nakka, Ramcharan Singh Angom, Santanu Bhattacharya, Krishnendu Pal, Debabrata Mukhopadhyay
2024-09-14 Reevaluating stemness in the intestinal crypt Samuel Asfaha, Nicola L. Jones
2024-09-14 Stress Ulcer Prophylaxis in the Intensive Care Unit – More Evidence of Benefit Rishad Khan
2024-09-14 EUS-guided Rendezvous versus Needle-knife Sphincterotomy Following Difficult Biliary Cannulation in ERCP for Benign Disease Nauzer Forbes
2024-09-13 Where do non-invasive colorectal cancer tools ‘FIT’ alongside colonoscopy in the surveillance of high-risk patients? Kevin J. Monahan
2024-09-12 AGA Clinical Practice Update on Integrating Potassium-Competitive Acid Blockers Into Clinical Practice: Expert Review Amit Patel, Loren Laine, Paul Moayyedi, Justin Wu
2024-09-08 Portal Fibrosis and the Ductular Reaction: Pathophysiological Role in the Progression of Liver Disease and Translational Opportunities Vikas Gupta, Tejasav S. Sehrawat, Massimo Pinzani, Mario Strazzabosco
2024-09-07 Risankizumab for Induction and Maintenance of Remission in Ulcerative Colitis Pavel S. Roshanov, Reena Khanna
2024-09-07 A Head-to Head Comparison of Risankizumab and Ustekinumab as Second-Line Therapy in Moderate to Severely Active Crohn’s Disease Pavel S. Roshanov, Reena Khanna
2024-09-07 Reply Ali Rezaie, Yee Hui Yeo
2024-09-07 Proteomic Biomarkers in Serum Predict Villous Atrophy Development in Asymptomatic Potential Celiac Disease Children at Time of Diagnosis Renata Auricchio, Roberta Mandile, Janneke Samsom, Chiara Esposito, Rossella de Cegli, Luigi Greco, European Laboratory for Food Induced Disease (ELFID) Group
2024-09-07 With Great Statistical Power Comes Great Responsibility: Pitfalls of Claims Database Research on the Periprocedural GLP-1 Receptor Agonist Management Debate Brent Hiramoto, Thomas R. Mccarty, Mayssan Muftah, Walter W. Chan
2024-09-07 Glucagon-Like Peptide 1 Receptor Agonists and Risk of Adverse Anesthesia Events: Caution Warranted When Interpreting Associations With Pulmonary Aspiration Inuk Zandvakili, Wei-Wen Hsu, Gregory G. Ginsberg
2024-09-07 Comments on “Metabolic Dysfunction–Associated Fibrosis 5 (MAF-5) Score Predicts Liver Fibrosis Risk and Outcome in the General Population With Metabolic Dysfunction” Yuting Guan, Jiaming Yang, Zudong Xu
2024-09-07 Pragmatic Resect and Discard Implementation Using Computer-Assisted Optical Polyp Diagnosis Mahsa Taghiakbari, Douglas K. Rex, Heiko Pohl, Roupen Djinbachian, Felix Huang, Cesare Hassan, Daniel Von Renteln
2024-09-07 Reply Laurens A. Van Kleef, Willem Pieter Brouwer
2024-09-05 Tofu-like Disfiguring Colitis Nie Kai, Zhao Lian, Wang Xiaoyan
2024-09-04 Intestinal Permeability in Disorders of Gut-Brain Interaction: From Bench to Bedside Madhusudan Grover, Tim Vanuytsel, Lin Chang
2024-09-04 Unveiling Cancer-Related Metaplastic Cells in Both Helicobacter pylori Infection and Autoimmune Gastritis Stella G. Hoft, Michelle Brennan, Javier A. Carrero, Nicholas M. Jackson, Challen A. Pretorius, Tarin M. Bigley, José B. Sáenz, Richard J. DiPaolo
2024-09-03 Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have a Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn’s Disease Pablo A. Olivera, Helena Martinez-Lozano, Haim Leibovitzh, Mingyue Xue, Anna Neustaeter, Osvaldo Espin-Garcia, Wei Xu, Karen L. Madsen, David S. Guttman, Charles N. Bernstein, Baruch Yerushalmi, Jeffrey S. Hyams, Maria T. Abreu, John K. Marshall, Iwona Wr
2024-08-31 Management of Small Bowel Crohn’s Disease Strictures: To Cut, to Stretch, or to Treat Inflammation? Cathy Lu, Brian G. Feagan, Joel G. Fletcher, Mark Baker, Stefan Holubar, Florian Rieder, Stenosis Therapy and Anti-Fibrosis Research Consortium
2024-08-31 Pancreatic Cancer–Induced Metabolic Dysregulation Syndrome: Clinical Profile, Proposed Mechanisms, and Unanswered Questions Lanisha Patterson, Frederico G.S. Toledo, Anirban Maitra, Suresh T. Chari
2024-08-31 Stool-Based Testing for Post-Polypectomy Colorectal Cancer Surveillance Safely Reduces Colonoscopies: The Molecular Stool Testing for Colorectal Cancer Surveillance Study Beatriz Carvalho, Willemijn de Klaver, Francine van Wifferen, Meta C.J. van Lanschot, Alouisa J.P. van Wetering, Quirine E.W. van der Zander, Margriet Lemmens, Anne S. Bolijn, Marianne Tijssen, Pien Delis-van Diemen, Nikkie Buekers, Kathleen Daenen, Jalee
2024-08-30 Corrigendum
2024-08-30 Reply Roupen Djinbachian, Douglas K. Rex, Daniel Von Renteln
2024-08-30 Effectiveness and Cost-Effectiveness of Colorectal Cancer Screening With a Blood Test That Meets the Centers for Medicare and Medicaid Services Coverage Decision Amar K. Das, Craig Eagle, Amirali Talasaz
2024-08-30 Reply Zainab Aziz, Sheila Rustgi, Chin Hur
2024-08-28 Combining Colonoscopy With Fecal Immunochemical Test Can Improve Current Familial Colorectal Cancer Colonoscopy Surveillance: A Modelling Study Francine Van Wifferen, Marjolein J.E. Greuter, Monique E. van Leerdam, Marcel B.W. Spanier, Evelien Dekker, Hans F.A. Vasen, Iris Lansdorp-Vogelaar, Karen Canfell, Gerrit A. Meijer, Tanya M. Bisseling, Nicoline Hoogerbrugge, Veerle M.H. Coupé
2024-08-28 Limitations in Autonomous Artificial Intelligence Optical Diagnosis Qi Mei, Poi Kuo, James Cheng-Chung Wei
2024-08-28 Reply Rosita Van Den Puttelaar, Pedro Nascimento De Lima, Iris Lansdorp-Vogelaar
2024-08-28 A Comparative Review of Autonomous Artificial Intelligence versus Artificial Intelligence–Assisted Human Optical Diagnosis of Colorectal Polyps Tiantian Cao, Chengqian Zhong
2024-08-28 Development and Validation of an Integrative Risk Score for Future Risk of Crohn’s Disease in Healthy First-Degree Relatives: A Multicentre Prospective Cohort Study Sun-Ho Lee, Williams Turpin, Osvaldo Espin-Garcia, Wei Xu, Kenneth Croitoru, Crohn’s Colitis Canada-Genetic, Environmental, Microbial Project Research Consortium
2024-08-28 Reply Uri Ladabaum, Ajitha Mannalithara, Robert E. Schoen, Jason A. Dominitz, David Lieberman
2024-08-28 Reply Roupen Djinbachian, Douglas K. Rex, Daniel Von Renteln
2024-08-27 A Rare Cause of liver injury in an adult Zixing Dai, Yuwen Li, Chuanlong Zhu
2024-08-26 Corrigendum
2024-08-23 Recompensation of Chronic Hepatitis C–Related Decompensated Cirrhosis Following Direct-Acting Antiviral Therapy: Prospective Cohort Study From a Hepatitis C Virus Elimination Program Madhumita Premkumar, Radha K. Dhiman, Ajay Duseja, Rohit Mehtani, Sunil Taneja, Ekta Gupta, Pankaj Gupta, Anchal Sandhu, Prerna Sharma, Sahaj Rathi, Nipun Verma, Anand V. Kulkarni, Harish Bhujade, Sreedhara B. Chaluvashetty, Naveen Kalra, Gagandeep S. Gro
2024-08-23 Exon-Skipping–Based Subtyping of Colorectal Cancers Aslihan Ambeskovic, Matthew N. McCall, Jonathan Woodsmith, Hartmut Juhl, Hartmut Land
2024-08-21 Crohn’s Patients and Healthy Infants Share Immunodominant B Cell Response to Commensal Flagellin Peptide Epitopes Qing Zhao, Lennard Wayne Duck, John T. Killian, Alexander F. Rosenberg, Peter J. Mannon, R. Glenn King, Lee A. Denson, Subra Kugathasan, Edward N. Janoff, Maria C. Jenmalm, Charles O. Elson
2024-08-21 Glutamine Supplementation as a Novel Metabolic Therapeutic Strategy for LIG3-Dependent Chronic Intestinal Pseudo-obstruction Chiara Diquigiovanni, Nicola Rizzardi, Erica Cataldi-Stagetti, Livia Gozzellino, Federica Isidori, Francesca Valenti, Arianna Orsini, Annalisa Astolfi, Tania Giangregorio, Loris Pironi, Elisa Boschetti, Serena Arrigo, Alessandra Maresca, Penelope Magnoni,
2024-08-20 Table of Contents
2024-08-20 Editorial Board
2024-08-20 Cover 1
2024-08-20 The Importance of Global Health Training in US-Based Gastroenterology and Hepatology Fellowship Programs Akwi W. Asombang, Mouhand F. Mohamed, Stella-Maris Chinma Egboh, Mmeyeneabasi Omede, Nkengeh Tazinkeng, Awab Ali Ibrahim
2024-08-20 Elsewhere in The AGA Journals (Preview Section)
2024-08-20 CME Exam 1: Portal Vein Thrombosis in the Setting of Cirrhosis: Evaluation and Management Strategies
2024-08-20 Unanticipated Findings With Upadacitinib Therapy Taylor A. Karl, McKinzie Johnson, Frank I. Scott
2024-08-17 Dietary Pattern Linking to Intestinal Microbial Characteristics and Colorectal Cancer Risk Jun Sun
2024-08-17 Gut Barrier Leakiness: Time to Take It Seriously? Javier Santos, Maria Rescigno
2024-08-16 Endoscopic Gastric Fundal Mucosal Ablation Induces Weight Loss in Adults With Obesity Daniel B. Maselli, Lauren L. Donnangelo, Chase Wooley, Christopher Chapman, Vivek Kumbhari, Christopher E. Mcgowan
2024-08-14 Effect of Enterotype-Dependent Stability of the Gut Microbiome on Postgastrectomy Malnutrition in Gastric Cancer Patients Han Na Oh, Woo Jun Sul, Sang-Yong Son, Sang-Uk Han, Hoon Hur, Sun Gyo Lim
2024-08-14 Spatially Resolved Niche and Tumor Microenvironmental Alterations in Gastric Cancer Peritoneal Metastases Joseph J. Zhao, Chin-Ann Johnny Ong, Supriya Srivatsava, Daryl Kai Ann Chia, Haoran Ma, Kiekyon Huang, Taotao Sheng, Kalpana Ramnarayanan, Xuewen Ong, Su Ting Tay, Takeshi Hagihara, Angie Lay Keng Tan, Melissa Ching Ching Teo, Qiu Xuan Tan, Gillian Ng, Jo
2024-08-13 AGA Clinical Practice Update on Pregnancy-Related Gastrointestinal and Liver Disease: Expert Review Shivangi Kothari, Yalda Afshar, Lawrence S. Friedman, Joseph Ahn
2024-08-10 Expanding the Diagnostic Toolkit in Chronic Cholestasis Nicholas Smith, Jennifer Borowsky, James A. Thomas
2024-08-09 Gluten-Dependent Activation of CD4+ T Cells by MHC Class II–Expressing Epithelium Sara Rahmani, Heather J. Galipeau, Alexandra V. Clarizio, Xuanyu Wang, Amber Hann, Gaston H. Rueda, Utkarshini N. Kirtikar, Marco Constante, Mark Wulczynski, Hsuan-Ming Su, Rebecca Burchett, Jonathan L. Bramson, Maria Ines Pinto-Sanchez, Juan Pablo Stefan
2024-08-08 Development and Implementation of a Clinical Decision Support Tool to Improve Adherence to Colonoscopy Follow-Up Guidelines Brian A. Sullivan, Hochong Gilles, Lyndsey Knauf, Steve S. Choi, Jill Moore, Jason A. Dominitz
2024-08-07 A Concerning Case of Severe Gastritis With Gastrointestinal Protein Loss Xinyu Liu, Hao Tang, Bei Tan
2024-08-06 An Empirical Dietary Pattern Associated with the Gut Microbial Features in Relation to Colorectal Cancer Risk Kai Wang, Chun-Han Lo, Raaj S. Mehta, Long H. Nguyen, Yiqing Wang, Wenjie Ma, Tomotaka Ugai, Hidetaka Kawamura, Satoko Ugai, Yasutoshi Takashima, Kosuke Mima, Kota Arima, Kazuo Okadome, Marios Giannakis, Cynthia L. Sears, Jeffrey A. Meyerhardt, Kimmie Ng,

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