JCI 今日热榜

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近期历史最近 100 条记录

2024-10-02	Sleepless nights and social plights: medial septum GABAergic hyperactivity in a neuroligin 3–deficient autism model	Claire E. Cho, Dahee Jung, Reesha R. Patel	
2024-10-02	Clonal hematopoiesis and atherosclerosis	Ohad Oren, Aeron M. Small, Peter Libby	
2024-10-02	Pediatric glioma immune profiling identifies TIM3 as a therapeutic target in BRAF fusion pilocytic astrocytoma	Shashwat Tripathi, Hinda Najem, Corey Dussold, Sebastian Pacheco, Ruochen Du, Moloud Sooreshjani, Lisa Hurley, James P. Chandler, Roger Stupp, Adam M. Sonabend, Craig M. Horbinski, Rimas V. Lukas, Joanne Xiu, Giselle Lopez, Theodore P. Nicolaides, Valerie	
2024-10-02	Distinct landscape and clinical implications of therapy-related clonal hematopoiesis	Koichi Takahashi, Daisuke Nakada, Margaret Goodell	
2024-10-02	The expanding application of antisense oligonucleotides to neurodegenerative diseases	Charlotte J. Sumner, Timothy M. Miller	
2024-10-02	Mucins protect against Streptococcus pneumoniae virulence by suppressing pneumolysin expression	Jade Bath, Elisabet Bjånes, Cengiz Goekeri, Jeff Hsiao, Deniz Uzun, Geraldine Nouailles, Victor Nizet, Katharina Ribbeck	
2024-10-02	Intertwining clonality and resistance: Staphylococcus aureus in the antibiotic era	Henry F. Chambers, Vance G. Fowler Jr	
2024-10-02	The first century of JCI and beyond	Elizabeth M. McNally	
2024-10-02	The emergence of clonal hematopoiesis as a disease determinant	Kenneth Walsh	
2024-10-02	The arc of discovery, from the description of cystic fibrosis to effective treatments	Michael J. Welsh	
2024-10-02	Toward a better understanding of chronic hepatitis B virus infection	Barbara Rehermann	
2024-10-02	The senescence-associated secretome of Hedgehog-deficient hepatocytes drives MASLD progression	Ji Hye Jun, Kuo Du, Rajesh Kumar Dutta, Raquel Maeso-Diaz, Seh Hoon Oh, Liuyang Wang, Guannan Gao, Ana Ferreira, Jon Hill, Steven S. Pullen, Anna Mae Diehl	
2024-10-02	Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer	Xiaolin Zhu, Tatyanah Farsh, Daniël Vis, Ivan Yu, Haolong Li, Tianyi Liu, Martin Sjöström, Raunak Shrestha, Jeroen Kneppers, Tesa Severson, Meng Zhang, Arian Lundberg, Thaidy Moreno Rodriguez, Alana S. Weinstein, Adam Foye, Niven Mehra, Rahul R. Aggarwal,	
2024-10-02	Viral infection induces inflammatory signals that coordinate YAP regulation of dysplastic cells in lung alveoli	Xiuyu Lin, Weicheng Chen, Guilin Yang, Jiazhu Zhang, Huilin Wang, Zeyu Liu, Ying Xi, Tao Ren, Bo Liu, Pengfei Sui	
2024-10-02	Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells	Chia-Lin Chen, Hidekazu Tsukamoto, Jian-Chang Liu, Claudine Kashiwabara, Douglas Feldman, Linda Sher, Steven Dooley, Samuel W. French, Lopa Mishra, Lydia Petrovic, Joseph H. Jeong, Keigo Machida	
2024-10-02	2024 Lasker Award Recipient Zhijian Chen elucidates how DNA stimulates immunity	Amy B. Heimberger	
2024-10-02	Joel Habener, Svetlana Mojsov, and Lotte Bjerre Knudsen awarded Lasker prize for pioneering work on GLP-1	Hossein Ardehali	
2024-10-02	IFN-γ and YAP lead epithelial cells astray after severe respiratory infection	Bradley E. Hiller, Joseph P. Mizgerd	
2024-10-02	Autism-associated neuroligin 3 deficiency in medial septum causes social deficits and sleep loss in mice	Haiyan Sun, Yu Shen, Pengtao Ni, Xin Liu, Yan Li, Zhentong Qiu, Jiawen Su, Yihan Wang, Miao Wu, Xiangxi Kong, Jun-Li Cao, Wei Xie, Shuming An	
2024-10-02	Neurosymptomatic HIV-1 CSF escape is associated with replication in CNS T cells and inflammation	Laura P. Kincer, Ameet Dravid, Mattia Trunfio, Andrea Calcagno, Shuntai Zhou, Riccardo Vercesi, Serena Spudich, Magnus Gisslen, Richard W. Price, Paola Cinque, Sarah B. Joseph	
2024-10-02	Ciliary localization of GPR75 promotes fat accumulation in mice	Marcelo Chávez, Anushweta Asthana, Peter K. Jackson	
2024-10-02	Single-cell multiomic analysis identifies macrophage subpopulations in promoting cardiac repair	Mingzhu Fu, Shengtao Jia, Longhui Xu, Xin Li, Yufang Lv, Yulong Zhong, Shanshan Ai	
2024-10-02	Quantifying variant contributions in cystic kidney disease using national-scale whole-genome sequencing	Omid Sadeghi-Alavijeh, Melanie M.Y. Chan, Gabriel T. Doctor, Catalin D. Voinescu, Alexander Stuckey, Athanasios Kousathanas, Alexander T. Ho, Horia C. Stanescu, Detlef Bockenhauer, Richard N. Sandford, Adam P. Levine, Daniel P. Gale	
2024-10-02	Central regulation of feeding and body weight by ciliary GPR75	Yiao Jiang, Yu Xun, Zhao Zhang	
2024-10-02	Clonal hematopoiesis and hematological malignancy	William G. Dunn, Matthew A. McLoughlin, George S. Vassiliou	
2024-10-02	IL-7–dependent and –independent lineages of IL-7R–dependent human T cells	Carlos A. Arango-Franco, Masato Ogishi, Susanne Unger, Ottavia M. Delmonte, Julio César Orrego, Ahmad Yatim, Margarita M. Velasquez-Lopera, Andrés F. Zea-Vera, Jonathan Bohlen, Marwa Chbihi, Antoine Fayand, Juan Pablo Sánchez, Julian Rojas, Yoann Seeleuth	
2024-09-18	F18-FDG PET imaging as a diagnostic tool for immune checkpoint inhibitor–associated acute kidney injury	Shruti Gupta, Olivia Green-Lingren, Sudhir Bhimaniya, Aleksandra Krokhmal, Heather Jacene, Marlies Ostermann, Sugama Chicklore, Ben Sprangers, Christophe M. Deroose, Sandra M. Herrmann, Sophia L. Wells, Sarah A. Kaunfer, Jessica L. Ortega, Clara García-Ca	
2024-09-18	Mechanisms underlying sex differences in autoimmunity	DeLisa Fairweather, Danielle J. Beetler, Elizabeth J. McCabe, Scott M. Lieberman	
2024-09-18	NKT cells promote Th1 immune bias to dengue virus that governs long-term protective antibody dynamics	Youngjoo Choi, Wilfried A.A. Saron, Aled O’Neill, Manouri Senanayake, Annelies Wilder-Smith, Abhay P.S. Rathore, Ashley L. St. John	
2024-09-18	Hif-2α programs oxygen chemosensitivity in chromaffin cells	Maria Prange-Barczynska, Holly A. Jones, Yoichiro Sugimoto, Xiaotong Cheng, Joanna D.C.C. Lima, Indrika Ratnayaka, Gillian Douglas, Keith J. Buckler, Peter J. Ratcliffe, Thomas P. Keeley, Tammie Bishop	
2024-09-18	Early ascertainment of genetic diagnoses clarifies impact on medium-term survival following neonatal congenital heart surgery	Benjamin J. Landis, Benjamin M. Helm, Matthew D. Durbin, Lindsey R. Helvaty, Jeremy L. Herrmann, Michael Johansen, Gabrielle C. Geddes, Stephanie M. Ware	
2024-09-18	Checkpoint therapy in cancer treatment: progress, challenges, and future directions	Mesude Bicak, Cansu Cimen Bozkus, Nina Bhardwaj	
2024-09-18	SARS-CoV-2 Delta and Omicron variants resist spike cleavage by human airway trypsin-like protease	Wenyan Ren, Weiqi Hong, Jingyun Yang, Jun Zou, Li Chen, Yanan Zhou, Hong Lei, Aqu Alu, Haiying Que, Yanqiu Gong, Zhenfei Bi, Cai He, Minyang Fu, Dandan Peng, Yun Yang, Wenhai Yu, Cong Tang, Qing Huang, Mengli Yang, Bai Li, Jingmei Li, Junbin Wang, Xuelei	
2024-09-18	The impact of sex on HIV immunopathogenesis and therapeutic interventions	Erin Mihealsick, Anna Word, Eileen P. Scully	
2024-09-18	ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts	Konrad Hoeft, Lars Koch, Susanne Ziegler, Ling Zhang, Steffen Luetke, Maria C. Tanzer, Debashish Mohanta, David Schumacher, Felix Schreibing, Qingqing Long, Hyojin Kim, Barbara M. Klinkhammer, Carla Schikarski, Sidrah Maryam, Mathijs Baens, Juliane Herman	
2024-09-18	Fibrosis uncovered: ADAMTS12 cuts to the core of extracellular matrix drama	Bernhard Dumoulin, Katalin Susztak	
2024-09-18	PRMT5-mediated FUBP1 methylation accelerates prostate cancer progression	Weiwei Yan, Xun Liu, Xuefeng Qiu, Xuebin Zhang, Jiahui Chen, Kai Xiao, Ping Wu, Chao Peng, Xiaolin Hu, Zengming Wang, Jun Qin, Liming Sun, Luonan Chen, Denglong Wu, Shengsong Huang, Lichen Yin, Zhenfei Li	
2024-09-18	Microbial mimics supersize the pathogenic self-response	Jesusa Capera, Michael L. Dustin	
2024-09-18	HLA A*24:02–restricted T cell receptors cross-recognize bacterial and preproinsulin peptides in type 1 diabetes	Garry Dolton, Anna Bulek, Aaron Wall, Hannah Thomas, Jade R. Hopkins, Cristina Rius, Sarah A.E. Galloway, Thomas Whalley, Li Rong Tan, Théo Morin, Nader Omidvar, Anna Fuller, Katie Topley, Md Samiul Hasan, Shikha Jain, Nirupa D’Souza, Thomas Hodges-Hoylan	
2024-09-18	Modulation of NOX2 causes obesity-mediated atrial fibrillation	Arvind Sridhar, Jaime DeSantiago, Hanna Chen, Mahmud Arif Pavel, Olivia Ly, Asia Owais, Miles Barney, Jordan Jousma, Sarath Babu Nukala, Khaled Abdelhady, Malek Massad, Lona Ernst Rizkallah, Sang-Ging Ong, Jalees Rehman, Dawood Darbar	
2024-09-18	Survival of men with metastatic hormone-sensitive prostate cancer and adrenal-permissive HSD3B1 inheritance	Nima Sharifi, Robert Diaz, Hui-Ming Lin, Evan Roberts, Lisa G. Horvath, Andrew Martin, Martin R. Stockler, Sonia Yip, Vinod V. Subhash, Neil Portman, Ian D. Davis, Christopher J. Sweeney	
2024-09-18	A correctable immune niche for epithelial stem cell reprogramming and post-viral lung diseases	Kangyun Wu, Yong Zhang, Huiqing Yin-DeClue, Kelly Sun, Dailing Mao, Kuangying Yang, Stephen R. Austin, Erika C. Crouch, Steven L. Brody, Derek E. Byers, Christy M. Hoffmann, Michael E. Hughes, Michael J. Holtzman	
2024-09-18	BCL2 expression is enriched in advanced prostate cancer with features of lineage plasticity	Daniel Westaby, Juan M. Jiménez-Vacas, Ines Figueiredo, Jan Rekowski, Claire Pettinger, Bora Gurel, Arian Lundberg, Denisa Bogdan, Lorenzo Buroni, Antje Neeb, Ana Padilha, Joe Taylor, Wanting Zeng, Souvik Das, Emily Hobern, Ruth Riisnaes, Mateus Crespo, S	
2024-09-18	TWIST1+FAP+ fibroblasts in the pathogenesis of intestinal fibrosis in Crohn’s disease	Yao Zhang, Jiaxin Wang, Hongxiang Sun, Zhenzhen Xun, Zirui He, Yizhou Zhao, Jingjing Qi, Sishen Sun, Qidi Yang, Yubei Gu, Ling Zhang, Chunhua Zhou, Youqiong Ye, Ningbo Wu, Duowu Zou, Bing Su	
2024-09-18	Teatime: epigallocatechin gallate targets fibroblast–epithelial cell crosstalk to combat lung fibrosis	Olivier Burgy, Melanie Königshoff	
2024-09-18	Exosomal TNF-α mediates voltage-gated Na+ channel 1.6 overexpression and contributes to brain tumor–induced neuronal hyperexcitability	Cesar Adolfo Sanchez Trivino, Renza Spelat, Federica Spada, Camilla D’Angelo, Ivana Manini, Irene Giulia Rolle, Tamara Ius, Pietro Parisse, Anna Menini, Daniela Cesselli, Miran Skrap, Fabrizia Cesca, Vincent Torre	
2024-09-18	UnTWISTing intestinal fibrosis: single-cell transcriptomics deciphers fibroblast heterogeneity, uncovers molecular pathways, and identifies therapeutic targets	Giovanni Santacroce, Antonio Di Sabatino	
2024-09-18	Reversible cold-induced lens opacity in a hibernator reveals a molecular target for treating cataracts	Hao Yang, Xiyuan Ping, Jiayue Zhou, Hailaiti Ailifeire, Jing Wu, Francisco M. Nadal-Nicolás, Kiyoharu J. Miyagishima, Jing Bao, Yuxin Huang, Yilei Cui, Xin Xing, Shiqiang Wang, Ke Yao, Wei Li, Xingchao Shentu	
2024-09-18	Connecting the dots: sex, depression, and musculoskeletal health	Mackenzie Newman, Henry J. Donahue, Gretchen N. Neigh	
2024-09-18	A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis	Max L. Cohen, Alexis N. Brumwell, Tsung Che Ho, Kiana Garakani, Genevieve Montas, Darren Leong, Vivianne W. Ding, Jeffrey A. Golden, Binh N. Trinh, David M. Jablons, Michael A. Matthay, Kirk D. Jones, Paul J. Wolters, Ying Wei, Harold A. Chapman, Claude J	
2024-09-18	Pericyte phenotype switching alleviates immunosuppression and sensitizes vascularized tumors to immunotherapy in preclinical models	Zhi-Jie Li, Bo He, Alice Domenichini, Jiulia Satiaputra, Kira H. Wood, Devina D. Lakhiani, Abate A. Bashaw, Lisa M. Nilsson, Ji Li, Edward R. Bastow, Anna Johansson-Percival, Elena Denisenko, Alistair R.R. Forrest, Suraj Sakaram, Rafael Carretero, Günter	
2024-09-18	Prebiotics improve frailty status in community-dwelling older individuals in a double-blind, randomized, controlled trial	Jie Yang, Liming Hou, Anhui Wang, Lei Shang, Xin Jia, Rong Xu, Xiaoming Wang	
2024-09-18	Teplizumab induces persistent changes in the antigen-specific repertoire in individuals at risk for type 1 diabetes	Ana Lledó-Delgado, Paula Preston-Hurlburt, Sophia Currie, Pamela Clark, Peter S. Linsley, S. Alice Long, Can Liu, Galina Koroleva, Andrew J. Martins, John S. Tsang, Kevan C. Herold	
2024-09-04	Guild-based approach for mitigating information loss and distortion issues in microbiome analysis	Liping Zhao, Guojun Wu, Naisi Zhao	
2024-09-04	Itm2a expression marks periosteal skeletal stem cells that contribute to bone fracture healing	Wenhui Xing, Heng Feng, Bo Jiang, Bo Gao, Jiping Liu, Zaiqi Xie, Yazhuo Zhang, Xuye Hu, Jun Sun, Matthew B. Greenblatt, Bo O. Zhou, Weiguo Zou	
2024-09-04	Increased risk of kidney failure in patients with genetic kidney disorders	Mark D. Elliott, Natalie Vena, Maddalena Marasa, Enrico Cocchi, Shiraz Bheda, Kelsie Bogyo, Ning Shang, Francesca Zanoni, Miguel Verbitsky, Chen Wang, Victoria Kolupaeva, Gina Jin, Maayan Sofer, Rafael Gras Pena, Pietro A. Canetta, Andrew S. Bomback, Lisa	
2024-09-04	Biallelic variants in RINT1 present as early-onset pure hereditary spastic paraplegia	Vicente Quiroz, Laura Planas-Serra, Abigail Sveden, Amy Tam, Hyo-Min Kim, Umar Zubair, Dario Resch, Afshin Saffari, Matt C. Danzi, Stephan Züchner, Maya Chopra, Luca Schierbaum, Aurora Pujol, Erik A. Eklund, Darius Ebrahimi-Fakhari	
2024-09-04	Relationship between maternal serotonin levels and autism-associated genetic variants	Amandeep Jutla, Lauren C. Shuffrey, Stephen J. Guter, Kally C. O’Reilly, George M. Anderson, James S. Sutcliffe, Edwin H. Cook, Jeremy Veenstra-VanderWeele	
2024-09-04	Hepatic lipopolysaccharide binding protein partially uncouples inflammation from fibrosis in MAFLD	Dan Wang, Ania Baghoomian, Zhengyi Zhang, Ya Cui, Emily C. Whang, Xiang Li, Josue Fraga, Rachel Ariana Spellman, Tien S. Dong, Wei Li, Arpana Gupta, Jihane N. Benhammou, Tamer Sallam	
2024-09-04	The cancer-associated secretory phenotype: a new frontier in targeted therapeutics	Xiaochao Tan, Guan-Yu Xiao, Priyam Banerjee, Shike Wang, Jonathan M. Kurie	
2024-09-04	Is it time to rethink the relationship between adipose inflammation and insulin resistance?	Evan D. Rosen, Shingo Kajimura	
2024-09-04	GLP-1R–positive neurons in the lateral septum mediate the anorectic and weight-lowering effects of liraglutide in mice	Zijun Chen, Xiaofei Deng, Cuijie Shi, Haiyang Jing, Yu Tian, Jiafeng Zhong, Gaowei Chen, Yunlong Xu, Yixiao Luo, Yingjie Zhu	
2024-09-04	Mapping the transcriptional evolution of human metastatic breast cancer	Melissa Q. Reeves	
2024-09-04	DRD2 activation inhibits choroidal neovascularization in patients with Parkinson’s disease and age-related macular degeneration	Thibaud Mathis, Florian Baudin, Anne-Sophie Mariet, Sébastien Augustin, Marion Bricout, Lauriane Przegralek, Christophe Roubeix, Éric Benzenine, Guillaume Blot, Caroline Nous, Laurent Kodjikian, Martine Mauget-Faÿsse, José-Alain Sahel, Robin Plevin, Chris	
2024-09-04	Cancer therapy–related salivary dysfunction	Cristina Paz, Annemarie Glassey, Abigail Frick, Sarah Sattar, Nicholas G. Zaorsky, Grace C. Blitzer, Randall J. Kimple	
2024-09-04	Revisiting sex as a biological variable in hypertension research	Michael J. Ryan, John S. Clemmer, Roy O. Mathew, Jessica L. Faulkner, Erin B. Taylor, Justine M. Abais-Battad, Fiona Hollis, Jennifer C. Sullivan	
2024-09-04	Disease-specific T cell receptors maintain pathogenic T helper cell responses in postinfectious Lyme arthritis	Johannes Dirks, Jonas Fischer, Julia Klaussner, Christine Hofmann, Annette Holl-Wieden, Viktoria Buck, Christian Klemann, Hermann J. Girschick, Ignazio Caruana, Florian Erhard, Henner Morbach	
2024-09-04	Unhealthy visceral fat is associated with improved efficacy of immunotherapy in endometrial cancer	Matthew L. Steinhauser	
2024-09-04	Type 1 innate lymphoid cells: a biomarker and therapeutic candidate in sarcoidosis	Inchul Cho, Andrew L. Ji	
2024-09-04	Somatic RAP1B gain-of-function variant underlies isolated thrombocytopenia and immunodeficiency	Marta Benavides-Nieto, Frédéric Adam, Emmanuel Martin, Charlotte Boussard, Chantal Lagresle-Peyrou, Isabelle Callebaut, Alexandre Kauskot, Christelle Repérant, Miao Feng, Jean-Claude Bordet, Martin Castelle, Guillaume Morelle, Chantal Brouzes, Mohammed Za	
2024-09-04	Metabolic benefits afforded by estradiol and testosterone in both sexes: clinical considerations	Franck Mauvais-Jarvis, Sarah H. Lindsey	
2024-09-04	Inflammation primes the murine kidney for recovery by activating AZIN1 adenosine-to-inosine editing	Segewkal Hawaze Heruye, Jered Myslinski, Chao Zeng, Amy Zollman, Shinichi Makino, Azuma Nanamatsu, Quoseena Mir, Sarath Chandra Janga, Emma H. Doud, Michael T. Eadon, Bernhard Maier, Michiaki Hamada, Tuan M. Tran, Pierre C. Dagher, Takashi Hato	
2024-09-04	Adeno-associated virus–based gene therapy treats inflammatory kidney disease in mice	Guochao Wu, Shuya Liu, Julia Hagenstein, Malik Alawi, Felicitas E. Hengel, Melanie Schaper, Nuray Akyüz, Zhouning Liao, Nicola Wanner, Nicola M. Tomas, Antonio Virgilio Failla, Judith Dierlamm, Jakob Körbelin, Shun Lu, Tobias B. Huber	
2024-09-04	Body mass index and adiposity influence responses to immune checkpoint inhibition in endometrial cancer	Nicolás Gómez-Banoy, Eduardo J. Ortiz, Caroline S. Jiang, Christian Dagher, Carlo Sevilla, Jeffrey Girshman, Andrew M. Pagano, Andrew J. Plodkowski, William A. Zammarrelli, Jennifer J. Mueller, Carol Aghajanian, Britta Weigelt, Vicky Makker, Paul Cohen, J	
2024-09-04	Recruitment of CXCR4+ type 1 innate lymphoid cells distinguishes sarcoidosis from other skin granulomatous diseases	Satish Sati, Jianhe Huang, Anna E. Kersh, Parker Jones, Olivia Ahart, Christina Murphy, Stephen M. Prouty, Matthew L. Hedberg, Vaibhav Jain, Simon G. Gregory, Denis H. Leung, John T. Seykora, Misha Rosenbach, Thomas H. Leung	
2024-09-04	Randomized controlled trial reveals no benefit to a 3-month delay in COVID-19 mRNA booster vaccine	Wen Shi Lee, Jennifer Audsley, Mai-Chi Trieu, Arnold Reynaldi, L. Carissa Aurelia, Palak H. Mehta, Joanne Patterson, Helen E. Kent, Julie Nguyen, Thakshila Amarasena, Robyn Esterbauer, Ebene R. Haycroft, Pradhipa Ramanathan, Miles P. Davenport, Timothy E.	
2024-09-04	Inhibiting the NADase CD38 improves cytomegalovirus-specific CD8+ T cell functionality and metabolism	Nils Mülling, Felix M. Behr, Graham A. Heieis, Kristina Boss, Suzanne van Duikeren, Floortje J. van Haften, Iris N. Pardieck, Esmé T.I. van der Gracht, Ward Vleeshouwers, Tetje C. van der Sluis, J. Fréderique de Graaf, Dominique M.B. Veerkamp, Kees L.M.C.	
2024-09-04	Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes	Juliane Winkler, Weilun Tan, Catherine M.M. Diadhiou, Christopher S. McGinnis, Aamna Abbasi, Saad Hasnain, Sophia Durney, Elena Atamaniuc, Daphne Superville, Leena Awni, Joyce V. Lee, Johanna H. Hinrichs, Patrick S. Wagner, Namrata Singh, Marco Y. Hein, M	
2024-09-04	Systemic and skin-limited delayed-type drug hypersensitivity reactions associate with distinct resident and recruited T cell subsets	Pranali N. Shah, George A. Romar, Artür Manukyan, Wei-Che Ko, Pei-Chen Hsieh, Gustavo A. Velasquez, Elisa M. Schunkert, Xiaopeng Fu, Indira Guleria, Roderick T. Bronson, Kevin Wei, Abigail H. Waldman, Frank R. Vleugels, Marilyn G. Liang, Anita Giobbie-Hur	
2024-09-04	Notch signaling suppresses neuroendocrine differentiation and alters the immune microenvironment in advanced prostate cancer	Sheng-Yu Ku, Yanqing Wang, Maria Mica Garcia, Yasutaka Yamada, Kei Mizuno, Mark D. Long, Spencer Rosario, Meenalakshmi Chinnam, Majd Al Assaad, Loredana Puca, Min Jin Kim, Martin K. Bakht, Varadha Balaji Venkadakrishnan, Brian D. Robinson, Andrés M. Acost	
2024-09-04	Pharmacologic LDH inhibition redirects intratumoral glucose uptake and improves antitumor immunity in solid tumor models	Svena Verma, Sadna Budhu, Inna Serganova, Lauren Dong, Levi M. Mangarin, Jonathan F. Khan, Mamadou A. Bah, Anais Assouvie, Yacine Marouf, Isabell Schulze, Roberta Zappasodi, Jedd D. Wolchok, Taha Merghoub	
2024-09-04	Wider recognition and greater understanding of postinfectious, antibiotic-refractory Lyme arthritis	Allen C. Steere, Jacob E. Lemieux	
2024-08-16	SLC44A2-mediated phenotypic switch of vascular smooth muscle cells contributes to aortic aneurysm	Mengen Xing, Wanqi Chen, Yachen Ji, Weihong Song	
2024-08-16	SLC44A2 regulates vascular smooth muscle cell phenotypic switching and aortic aneurysm	Tianyu Song, Shuang Zhao, Shanshan Luo, Chuansheng Chen, Xingeng Liu, Xiaoqi Wu, Zhongxu Sun, Jiawei Cao, Ziyu Wang, Yineng Wang, Bo Yu, Zhiren Zhang, Xiaolong Du, Xiaoqiang Li, Zhijian Han, Hongshan Chen, Feng Chen, Liansheng Wang, Hong Wang, Kangyun Sun	
2024-08-16	The NR4A2/VGF pathway fuels inflammation-induced neurodegeneration via promoting neuronal glycolysis	Marcel S. Woo, Lukas C. Bal, Ingo Winschel, Elias Manca, Mark Walkenhorst, Bachar Sevgili, Jana K. Sonner, Giovanni Di Liberto, Christina Mayer, Lars Binkle-Ladisch, Nicola Rothammer, Lisa Unger, Lukas Raich, Alexandros Hadjilaou, Barbara Noli, Antonio L.	
2024-08-16	Neutrophils insert elastase into hepatocytes to regulate calcium signaling in alcohol-associated hepatitis	Noriyoshi Ogino, M. Fatima Leite, Mateus T. Guerra, Emma Kruglov, Hiromitsu Asashima, David A. Hafler, Takeshi Ito, João P. Pereira, Brandon J. Peiffer, Zhaoli Sun, Barbara E. Ehrlich, Michael H. Nathanson	
2024-08-16	LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes	Jingzhong Ding, Anh Tram Nguyen, Kurt Lohman, Michael T. Hensley, Daniel Parker, Li Hou, Jackson Taylor, Deepak Voora, Janet K. Sawyer, Elena Boudyguina, Michael P. Bancks, Alain Bertoni, James S. Pankow, Jerome I. Rotter, Mark O. Goodarzi, Russell P. Tra	
2024-08-16	Potentiation of BKCa channels by cystic fibrosis transmembrane conductance regulator correctors VX-445 and VX-121	Aaron Kolski-Andreaco, Stefanie Taiclet, Michael M. Myerburg, John Sembrat, Robert J. Bridges, Adam C. Straub, Zachary P. Wills, Michael B. Butterworth, Daniel C. Devor	
2024-08-16	Intercellular interaction between FAP+ fibroblasts and CD150+ inflammatory monocytes mediates fibrostenosis in Crohn’s disease	Bo-Jun Ke, Saeed Abdurahiman, Francesca Biscu, Gaia Zanella, Gabriele Dragoni, Sneha Santhosh, Veronica De Simone, Anissa Zouzaf, Lies van Baarle, Michelle Stakenborg, Veronika Bosáková, Yentl Van Rymenant, Emile Verhulst, Sare Verstockt, Elliott Klein, G	
2024-08-16	MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunction	Natalie M. Walker, Yuta Ibuki, A. Patrick McLinden, Keizo Misumi, Dylan C. Mitchell, Gabriel G. Kleer, Alison M. Lock, Ragini Vittal, Nahum Sonenberg, Amanda L. Garner, Vibha N. Lama	
2024-08-16	The forgotten pandemic: how understanding cholera illuminated mechanisms of chloride channels in multiple diseases	Qais Al-Awqati	
2024-08-16	CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target	Quy Le, Brandon Hadland, Jenny L. Smith, Amanda Leonti, Benjamin J. Huang, Rhonda Ries, Tiffany A. Hylkema, Sommer Castro, Thao T. Tang, Cyd N. McKay, LaKeisha Perkins, Laura Pardo, Jay Sarthy, Amy K. Beckman, Robin Williams, Rhonda Idemmili, Scott Furlan	
2024-08-16	Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1	Callum Beach, David MacLean, Dominika Majorova, Stavros Melemenidis, Dhanya K. Nambiar, Ryan K. Kim, Gabriel N. Valbuena, Silvia Guglietta, Carsten Krieg, Mahnaz Darvish-Damavandi, Tatsuya Suwa, Alistair Easton, Lily V.S. Hillson, Ashley K. McCulloch, Ros	
2024-08-16	The Alzheimer’s disease–linked protease BACE2 cleaves VEGFR3 and modulates its signaling	Andree Schmidt, Brian Hrupka, Frauke van Bebber, Sanjay Sunil Kumar, Xiao Feng, Sarah K. Tschirner, Marlene Aßfalg, Stephan A. Müller, Laura Sophie Hilger, Laura I. Hofmann, Martina Pigoni, Georg Jocher, Iryna Voytyuk, Emily L. Self, Mana Ito, Kana Hyakko	
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